Preterm birth (PTB) remains the major cause of neonatal morbidity and mortality. For the vast majority of spontaneous PTBs, the final pathway is opening of the cervix. Pessaries have been proposed since the 1950s as a possible intervention to keep the cervix closed. But are pessaries safe and do they work for prevention of spontaneous PTB?
Vincenzo Berghella, MD
If a patient with a prior spontaneous preterm birth presents at 24 weeks, should you test fibronectin levels to determine her risk of another preterm delivery?