A direct association exists between endometrial cancer risk and individual components of the metabolic syndrome beyond simply being overweight, according to a case-control study.
A direct association exists between endometrial cancer risk and individual components of the metabolic syndrome (MetS) beyond simply being overweight, according to a case-control study of more than 1,200 women in Italy.
Researchers found that women with type 2 diabetes mellitus were more than twice as likely as those without the disease to develop endometrial cancer (odds ratio [OR], 2.18).
In addition, the ORs for developing endometrial cancer were 1.77 for women with hypertension, 1.20 for women with hyperlipidemia, between 1.62 and 2.23 for women who fit various definitions of central obesity, and 3.83 for women with a body mass index (BMI) greater than 30 kg/m2.
Rosato V, Zucchetto A, Bosetti C, et al. Metabolic syndrome and endometrial cancer risk. Ann Oncol. October 11, 2010. Epub ahead of print.
A Legacy of Excellence: Reflecting on the Final Print Edition of Contemporary OB/GYN
April 25th 2025Marking the end of an era and the beginning of a new chapter, the final print edition of Contemporary OB/GYN celebrates over 50 years of evidence-based guidance and unwavering support for clinicians.
Read More