Improving pediatric HPV vaccination rates: Early initiation and addressing disparities
December 17th 2024A quality improvement project highlights the benefits of starting human papillomavirus vaccination at age 9 years to increase uptake and reduce disparities in cancer prevention across pediatric populations.
Addressing Challenges in Accessing Traditional STI Screening Options
December 3rd 2024The panelist discusses how asymptomatic sexually transmitted infections (STIs) can silently impact overall health, emphasizing the importance of comprehensive screening and education, particularly for less known STIs like trichomoniasis and Mycoplasma genitalium, while exploring how newer testing methods like nucleic acid amplification testing (NAAT) can address challenges in traditional screening access and improve patient care.
Guidance for PCPs: Streamlining Menopause Care
December 2nd 2024Panelists discuss strategies for simplifying complex information for primary care physicians (PCPs), provide tips on how PCPs can effectively communicate evidence-based treatment options to patients, and outline actionable points and key takeaways to enhance patient care in managing menopause symptoms.
Nonestrogen Treatments for Menopause
December 2nd 2024Panelists discuss alternative therapies for women who are not candidates for or choose not to use hormonal therapy, review nonhormonal treatment options recommended by the North American Menopause Society, and explore the growing importance of Level I evidence and consensus opinions in creating a more holistic view of available therapies, both hormonal and nonhormonal.
Malignancy Risks of Neurokinin Receptor Antagonists
December 2nd 2024Panelists discuss clinical trial data suggesting a small but higher incidence of endometrial hyperplasia or malignancy with fezolinetant, while no cases of endometrial hyperplasia or malignancy were observed with elinzanetant in a long-term safety study.
Molecular Comparison and Safety Profiles of Fezolinetant and Elinzanetant
December 2nd 2024Panelists discuss why elinzanetant is likely to be associated with a lower risk of liver injury due to its distinct molecular structure compared to fezolinetant, and compare the adverse event profiles of the 2 drugs, highlighting that elinzanetant is more commonly associated with headache and fatigue while fezolinetant is linked to abdominal pain, diarrhea, insomnia, and back pain.
Fezolinetant Guidelines and Emerging Data on Menopause and Liver Health
December 2nd 2024Panelists discuss why a warning about serious liver injury was added to the prescribing information for fezolinetant following a postmarketing case of drug-induced liver injury, and review updated guidelines for baseline liver testing, recommended monitoring, symptoms indicating the need to discontinue the medication, and key points for addressing patient concerns about liver health.
Neurokinin and Estrogen Balance in Menopausal Hot Flashes for Primary Care
December 2nd 2024Panelists discuss how to simplify the physiology of KNDy neurons and neurokinin (NK) receptors for primary care physicians, explaining how NK3 antagonism reduces hot flashes, while NK1 antagonism helps alleviate sleep disturbances and night sweats, with fezolinetant and elinzanetant serving as key nonhormonal treatment options.
Importance of STI Screening to Detect Uncommon Infections
November 27th 2024Kameelah Phillips, MD, FACOG, NCMP, discusses how advances in molecular testing have improved the diagnosis and management of vaginitis and sexually transmitted infections like Mycoplasma genitalium and trichomoniasis, emphasizing the importance of education and awareness to promote better screening practices.
VMS Symptoms and Neurokinin Receptor Antagonists
November 25th 2024Panelists discuss how neurokinin 3 (NK3) receptors contribute to vasomotor symptoms (VMS) and how antagonism of NK3 receptors with drugs like fezolinetant can effectively reduce VMS, while also exploring the dual receptor action of elinzanetant, which blocks both NK1 and NK3 receptors to improve VMS and associated sleep disturbances.
Understanding and managing postpartum hemorrhage: Insights from Kameelah Phillips, MD
November 8th 2024Learn why postpartum hemorrhage remains a critical maternal health issue in the United States and discover effective treatment approaches and preventative strategies shared by expert ob-gyn Kameelah Phillips, MD.