News: Flaxseed reduces total/LDL cholesterol levels in postmenopause

Article

Three months of dietary supplementation with flaxseed lowered total and low-density lipoprotein cholesterol levels.

Three months of dietary supplementation with flaxseed, 30 g/d, lowered the total and low-density lipoprotein cholesterol (LDL-C) levels of Native American postmenopausal women by approximately 7% and 10%, respectively.

Researchers from Oklahoma, Arkansas, and Florida included 55 mildly to moderately hypercholesterolemic (≥5.1 to ≤9.8 mmol/L) Native American postmenopausal women in the study. The flaxseed provided was incorporated into baking products, such as breads and muffins, rather than consumed as a whole ground food, on the belief that the cholesterol lowering effects of flaxseed are enhanced by the high temperatures associated with baking.

No statistically significant changes in high-density lipoprotein (HDL) or triglyceride levels occurred; however, triglyceride concentrations in the flaxseed group increased insignificantly, suggesting that the n-3 fatty acid in flaxseed, unlike that of fish oil, is ineffective in lowering triglyceride levels. Flaxseed also lowered Lp(a), an independent predictor of atherosclerosis, by 22%, although the mean values did not reach statistical significance. Flaxseed had no effect on hematologic parameters, such as white or red blood cell counts or hemoglobin concentrations, but it did increase monocyte percentage, which theoretically leads to greater uptake of cholesterol from plasma and more plaque formation. And it had no effect on serum levels of C-reactive protein or on estrogen or FSH levels.

Patade A, Devareddy L, Lucas EA, et al. Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women. J Womens Health (Larchmt). 2008;17:355-366.

Recent Videos
Revi System shows efficacy against urgency urinary incontinence | Image Credit: ics.org.
1 expert is featured in this series.
Researchers highlight risks of breastfeeding while taking Levetiracetam | Image Credit: uwaterloo.ca.
Ipek Ensari, PhD, highlights improved mental health in chronic pelvic pain from physical activity | Image Credit: scholars.mssm.edu
New pSNM system empowers patients in urge urinary incontinence treatment | Image Credit: trinityhealthmichigan.org.
Jannah Thompson, MD, highlights battery free device for UUI management | Image Credit: trinityhealthmichigan.org
Anietie Aliu, PhD, highlights racial barriers to breast cancer screening | Image Credit: bbc.com.
Anietie Aliu, PhD, discusses how to improve breast cancer screening disparities | Image Credit: bbc.com
Jennifer Payne, MD, highlights how to help young women with perimenopause symptoms | Image Credit: uvahealth.com/findadoctor.
Perimenopausal symptoms in young women discussed by Jennifer Payne, MD | Image Credit: uvahealth.com/findadoctor.
Related Content
© 2025 MJH Life Sciences

All rights reserved.