Revi System shows efficacy against urgency urinary incontinence

In a recent interview with Contemporary OB/GYN, John PFA Heesakkers, MD, PhD, MBA, with Maastricht Universitair Medisch Centrum, discussed the results of a study evaluating the efficacy of the Revi System, a neuromodulation-based treatment for urgency urinary incontinence.

The study, which has data from a 2-year period, included 150 participants and focused on the long-term effectiveness of the Revi System. Early in the study, a smaller cohort was used to examine the system's safety, and the results indicated that it was safe to use. While the initial aim was to assess safety, the secondary goal of evaluating efficacy showed promising results.

Heesakkers reported that after 2 years, 79% of participants experienced a reduction of more than 50% in urinary incontinence episodes, demonstrating the Revi System's effectiveness in addressing the condition. This long-term data is particularly notable as it suggests the system offers a durable solution to a common and often distressing medical issue.

Urgency urinary incontinence, which involves an unpredictable and often sudden need to urinate, was highlighted by Heesakkers as a condition that significantly impacts patients' quality of life. For individuals suffering from this condition, the unpredictability of symptoms may lead to embarrassing accidents, such as wetting oneself if a bathroom is not available in time. This leads many individuals to avoid social situations or public outings, further diminishing their quality of life. The Revi System, according to Heesakkers, helps to reduce these incidents by improving bladder control, which in turn alleviates the fear of accidents and allows patients to lead more confident, active lives.

Heesakkers also mentioned the limitations of current treatments for overactive bladder, such as anticholinergic medications. While these drugs are often prescribed to manage the symptoms, they may cause side effects such as dry mouth, constipation, and cognitive issues. Additionally, for older patients who already take other medications, these drugs may interfere with other treatments, making patients hesitant to rely on them. In contrast, the Revi System offers a side-effect-free alternative that does not require daily medication, making it a more appealing option for many patients.

Heesakkers emphasized the positive feedback from patients, noting that after 2 years, 97% of participants expressed satisfaction with the treatment. This high level of patient satisfaction, alongside the lack of significant side effects, makes the Revi System a promising option for both patients and health care providers. The system's ease of application and effectiveness in patients who may not be suited for other treatments further increases its appeal. Overall, the study results demonstrated that the Revi System is a highly effective, patient-friendly treatment for managing urgency urinary incontinence.

Reference

Heesakkers JPFA, Toozs-Hobson P, Sutherland SE, et al. Two-year efficacy and safety outcomes of the pivotal OASIS study using the Revi System for treatment of urgency urinary incontinence. Journal of Urology. 2025;213(3):323–32. doi:10.1097/JU.0000000000004328