Study: Higher BMI associated with reduced breast Ca risk in premenopausal women
July 3rd 2018While obesity has been shown to have a strong correlation with an increased risk of breast cancer in postmenopausal women, the results from a large-scale, multicenter analysis show that the inverse may actually be true for younger women. PLUS: Women with denser breast tissue have higher recall and biopsy rates and increased odds of screen-detected and interval breast cancer, according to a recent study.
Study: Candidiasis drug increases risk of spontaneous abortion
June 26th 2018An analysis by Danish investigators published in JAMA shows that taking oral fluconazole during pregnancy is associated with a significant increased risk of spontaneous abortion. Plus: What persuades parents to vaccinate for HPV? Also: Does prenatal exposure to lithium increase risk of congenital malformations?
Legally Speaking: Uterine rupture
June 19th 2018A patient filed a lawsuit on behalf of her child alleging negligence by her obstetrician in delaying the delivery when she was in the hospital contracting and had severe abdominal pain. Thus, her uterus was allowed to rupture, which caused the child’s severe brain injury. Plus more malpractice cases.
Study: Mifepristone pretreatment improves management of first-trimester pregnancy loss
June 19th 2018A recent study compared pretreatment with mifepristone followed by treatment with misoprostol against treating with misoprostol alone for the management of first-trimester pregnancy loss. Plus: Are patients less satisfied with MDs who reduce opioids? Also: Does infant exposure to hypertensive disorders or pregnancy affect neurodevelopment?
Sepsis and septic shock in pregnancy
June 18th 2018Recognition and management of sepsis and septic shock in pregnant women remain a challenge, despite several advances made in the non-pregnant patient population. This article will review how to recognize sepsis and key principles for management of the condition in pregnant patients.
Investigational 17β-estradiol vaginal capsule relieves dyspareunia and vaginal dryness
June 14th 2018The experimental agent TX-004HR effectively improved the vaginal mucosa of postmenopausal women with vulvovaginal atrophy (VVA) and reduced moderate-to-severe dyspareunia and vaginal dryness compared to placebo, according to results of a trial.
Does ‘prevention first’ approach to UTI with cranberry juice have benefits?
June 14th 2018Results of a study by Canadian researchers suggest that exposure to low and medium doses of cranberry juice may have potential to reduce physician visits and costs for women who have a history of recurrent urinary tract infection (UTI).
TAILORx trial finds chemotherapy not beneficial for all breast cancer patients
June 12th 2018According to research recently published in The New England Journal of Medicine, chemotherapy is not more beneficial than treatment with hormone therapy alone for women with certain types of breast cancer. Plus: Do abortions cause depression? Also: Public comments are being solicited on a new systematic review from the US Preventive Services Task Force (USPSTF) on unhealthy alcohol use in adults aged 18 and older, including pregnant women.
Self-Administered Questionnaire Captures Symptoms of Endometriosis Pain
June 6th 2018A new self-administered scale to assess painful symptoms of endometriosis in research trials was recently developed by European obstetrician/gynecologists, the first time such a scale has been created with input from both clinicians and patients.
Live birth in world’s first in utero stem cell transplant trial
June 5th 2018The first birth from a groundbreaking trial of in utero stem cell transplantation suggests that fetal therapy may be a viable new option for alpha thalassemia (ATM). Plus: Why do vasomotor symptoms bother some women long after menopause? Also: Does CPAP improve sexual QOL in women with sleep apnea?
Is there a preterm placental microbiome?
May 29th 2018Results of a UK study show that while intrauterine infection may contribute to preterm birth (PTB), a reproducible “preterm placental microbiome” does not exist. Plus: Depression in the male partner of couples being treated for infertility was linked to lower pregnancy chances, according to results of a recent study.
Study: Prenatal tobacco, marijuana use can affect infant size, behavior
May 22nd 2018Prenatal exposure to tobacco and marijuana can affect infant size and behavior, according to a recently published study. Plus: Is HT-NIPT cost-effective for guiding postpartum use of anti-D? Also: A recent study shows that lesbian and bisexual (LB) women have a greater likelihood of developing type 2 diabetes (T2D) than their heterosexual counterparts.