Oxytocin suspect in cases with poor outcomes
July 11th 2018Oxytocin is one of the most frequently used drugs during labor but it can also become a major issue in a malpractice case filed after a labor and delivery if there is an adverse outcome. PLUS: Carolyn Zelop, MD, provides commentary on a lawsuit involving a patient death during pregnancy due to cardiomyopathy.
Pilot study finds oral SERM improves pain and sexual function
July 11th 2018An oral selective estrogen receptor modulator approved for treatment of mild to moderate dyspareunia in menopausal women reduced signs and symptoms of atrophy in the vulva, vestibule, urethral meatus and vagina region, according to results of a prospective open-label pilot study
Genetic testing plus mammography beneficial for determining breast cancer risk in younger women
July 10th 2018Mammography is sufficient to predict breast cancer risk in women aged ≥ 60, but in younger women, combining mammography and genetic testing improves the assessment, according to a retrospective case-control study
Fertility banking – how secure is it?
July 10th 2018Recent cryopreservation tank failures have focused a spotlight on procedures used by IVF facilities to safeguard patients’ reproductive tissue. The information here may help ob/gyns and their patients better understand the processes, management, and maintenance of IVF systems.
Does a mother’s diet influence her infant’s gut microbiome?
July 10th 2018A study by investigators from New England suggests that a mother’s diet during pregnancy and lactation may have an impact on the microbiome in her infant’s gut. PLUS: Are prenatal vitamin D levels tied to adverse pregnancy outcomes? ALSO: Results of a survey-based study of attending surgeons shows that they play a major role in whether women with breast cancer receive genetic testing.
Study: Higher BMI associated with reduced breast Ca risk in premenopausal women
July 3rd 2018While obesity has been shown to have a strong correlation with an increased risk of breast cancer in postmenopausal women, the results from a large-scale, multicenter analysis show that the inverse may actually be true for younger women. PLUS: Women with denser breast tissue have higher recall and biopsy rates and increased odds of screen-detected and interval breast cancer, according to a recent study.
Study: Candidiasis drug increases risk of spontaneous abortion
June 26th 2018An analysis by Danish investigators published in JAMA shows that taking oral fluconazole during pregnancy is associated with a significant increased risk of spontaneous abortion. Plus: What persuades parents to vaccinate for HPV? Also: Does prenatal exposure to lithium increase risk of congenital malformations?
Legally Speaking: Uterine rupture
June 19th 2018A patient filed a lawsuit on behalf of her child alleging negligence by her obstetrician in delaying the delivery when she was in the hospital contracting and had severe abdominal pain. Thus, her uterus was allowed to rupture, which caused the child’s severe brain injury. Plus more malpractice cases.
Study: Mifepristone pretreatment improves management of first-trimester pregnancy loss
June 19th 2018A recent study compared pretreatment with mifepristone followed by treatment with misoprostol against treating with misoprostol alone for the management of first-trimester pregnancy loss. Plus: Are patients less satisfied with MDs who reduce opioids? Also: Does infant exposure to hypertensive disorders or pregnancy affect neurodevelopment?
Sepsis and septic shock in pregnancy
June 18th 2018Recognition and management of sepsis and septic shock in pregnant women remain a challenge, despite several advances made in the non-pregnant patient population. This article will review how to recognize sepsis and key principles for management of the condition in pregnant patients.
Investigational 17β-estradiol vaginal capsule relieves dyspareunia and vaginal dryness
June 14th 2018The experimental agent TX-004HR effectively improved the vaginal mucosa of postmenopausal women with vulvovaginal atrophy (VVA) and reduced moderate-to-severe dyspareunia and vaginal dryness compared to placebo, according to results of a trial.
Does ‘prevention first’ approach to UTI with cranberry juice have benefits?
June 14th 2018Results of a study by Canadian researchers suggest that exposure to low and medium doses of cranberry juice may have potential to reduce physician visits and costs for women who have a history of recurrent urinary tract infection (UTI).
TAILORx trial finds chemotherapy not beneficial for all breast cancer patients
June 12th 2018According to research recently published in The New England Journal of Medicine, chemotherapy is not more beneficial than treatment with hormone therapy alone for women with certain types of breast cancer. Plus: Do abortions cause depression? Also: Public comments are being solicited on a new systematic review from the US Preventive Services Task Force (USPSTF) on unhealthy alcohol use in adults aged 18 and older, including pregnant women.