Editorial: Who will follow in our footsteps?
June 1st 2005As I write this I am post-call, which may account for the tone of my meandering discourse. At my age, the problem is not so much taking call but surviving the next day. While tackling clinical challenges can be exciting, what I find most stimulating is the chance to teach and learn from my residents.
Redefining the Family Cancer History
May 12th 2005There's a good chance that you are asking the wrong questions and not enough questions when it comes to taking family cancer histories. "It is not enough to ask 'Did anybody in your family die of cancer, yes or no?'" said Louise Strong, MD, Section Head of Clinical Cancer Genetics and Professor of Cancer Genetics at the University of Texas M.D. Anderson Cancer Center in Houston, TX.
1-Year Results Favor Monthly Ibandronate Dosing Over Daily
May 12th 2005First-year data from the 2-year MOBILE study of monthly administration of ibandronate for postmenopausal osteoporosis have been released. All women achieved significant response, but women taking the agent once a month had a greater increase in bone mineral density (BMD) than similar women taking the drug on a daily schedule.
Women Prefer Monthly Dosing for Osteoporosis
May 12th 2005Women being treated for osteoporosis expressed an overwhelming preference for monthly dosing over weekly dosing in a recent nationwide survey. The study, directed by Wulf Utian of The Cleveland Clinic in Cleveland, OH, supports the monthly dosing schedule offered by ibandronate, a competing oral bisphosphonate.
BMD Recovers After Discontinuing DMPA Contraception
May 11th 2005Intramuscular injection of depot medroxyprogesterone acetate (DMPA) is a highly effective and popular form of contraception. It is used by about 2 million women in the US and 25 million women worldwide, according to Andrew Kaunitz, MD, from the University of Florida Health Science Center in Jacksonville, FL.
Concomitant Tubal Sterilization and Endometrial Ablation Safe
May 11th 2005Is concomitant sterilization using the ESSURE method with Thermachoice III endometrial ablation feasible and safe? Absolutely yes, said Rafael Valle, MD, from Northwestern University Medical School in Chicago. Data presented during the second session of Papers on Current Clinical and Basic Investigation yesterday afternoon helped convince the Food and Drug Administration to approve the combination procedure.
Uterine Fibroid Embolization Most Cost-Effective Treatment
May 11th 2005Cost effectiveness may change the way physicians treat uterine fibroids. The newest procedure, uterine fibroid embolization (UFE) offers financial advantages over hysterectomy or myomectomy for insurers, hospitals, and the health-care system.
Cryoablation Benefits Continue Into Second Year
May 11th 2005Cryoablation has been reported as an effective treatment for abnormal uterine bleeding in the short term, but longer-term data have been lacking. New data from Raffaele Bruno, MD, and a research team at Lahey Clinic in Burlington, MA, indicate that cryoabalation is also effective into the second year after treatment.
Hormone Choice Can Affect Bleeding Patterns in Continuous OC
May 11th 2005A growing number of physicians and patients are looking to continuous use of oral contraceptives (OCs) to reduce the number of menstrual days and provide other quality-of-life improvements. But there are unanswered questions about the effect of different hormones used in OC on bleeding patterns.
Lasofoxifene Improves Vaginal Atrophy in Phase III Trial
May 11th 2005Phase II studies have shown that lasofoxifene, a next-generation selective estrogen-receptor modulator, increased bone mineral density and improved both objective measures of vaginal atrophy and reported symptoms. Margery Gass, MD, and a team from the University of Cincinnati Medical Center reported yesterday that a double-blind, randomized, placebo-controlled Phase III trial produced similar results.
Lasofoxifene Effective for Dyspareunia
May 10th 2005Dyspareunia is a significant problem in postmenopausal women. A recent study at George Washington University found that up to 92% of sexually active women reported moderate or severe symptoms. Forty percent of women cited dyspareunia as their most bothersome problem associated with vaginal atrophy. A recent Phase III trial showed that lasofoxifene can significantly improve the symptoms of dyspareunia as well as increase bone mineral density (BMD) in postmenopausal women.
Earlier is Better in Prenatal Diagnosis
May 10th 2005There is no such thing as too early when it comes to prenatal screening and diagnosis of chromosomal abnormalities. For women under 35, the American College of Obstetricians and Gynecologists (ACOG) has long recommended noninvasive screening in the second trimester. For older women, chorionic villus sampling (CVS) or amniocentesis were typically recommended, although these invasive procedures are now offered to women of any age during the second trimester.
Preterm Delivery A Heritable Trait
May 10th 2005Analysis of preterm delivery (PTD) patterns among Mormon women in Utah and surrounding states indicates that genetics play a leading role in preterm delivery. If the genetic link holds, obstetricians can expect to see even higher rates of PTD in future years.
Lasofoxifene Effective for Dyspareunia
May 10th 2005Dyspareunia is a significant problem in postmenopausal women. A recent study at George Washington University found that up to 92% of sexually active women reported moderate or severe symptoms. Forty percent of women cited dyspareunia as their most bothersome problem associated with vaginal atrophy. A recent Phase III trial showed that lasofoxifene can significantly improve the symptoms of dyspareunia as well as increase bone mineral density (BMD) in postmenopausal women.
Fewer Pap Tests More Cost-Effective for Some Middle-Aged Women
May 10th 2005Many middle-aged women are getting more Pap tests than they need. Women aged 45 to 60 are typically advised to get an annual Pap test, noted George Sawaya, MD, Associate Professor of Obstetrics, Gynecology, and Reproductive Science at the University of California San Francisco. But in a paper presented yesterday, Dr. Sawaya concluded that women with a history of three or more normal Paps should only be screened once every 3 years.
Triplet Ultrasound Growth Curves Mapped
May 10th 2005The identification of abnormal growth in triplet fetuses has been difficult because there have been no standards for comparison. A study at Tufts-New England Medical Center in Boston has produced curves for growth as measured by estimated fetal weight, abdominal circumference, biparietal diameter, head circumference, and femur length. All measurements were conducted sonographically.
Invitation to Gyn Exam Effective
May 10th 2005Do even half of your patients keep their appointments for annual gynecologic exams? Compliance with annual checkups is so poor that most ob/gyns would have to answer "no." Boris Petrikovsky, MD, PhD, and a research team at Nassau University Medical Center in East Meadow, NY, found that simply inviting women to visit their physician can boost compliance rates by nearly a third.
Meeting Preview: Monday, May 9, 2005
May 8th 2005The ACM got off to a strong start at 8:30 am with the opening ceremony and first scientific session, better known as the President's Program. This year's program focuses on Sex, Power, and Politics. Malcolm Potts, MB, BChir, PhD, FRCOG, leads off with the Samuel A. Cosgrove Memorial Lecture, asking the provocative question "Why Can't a Man Be More Like a Woman? The Behavioral Background of Ob-Gyn Practice."