Hormone-sensing pathway may explain gender biases in fungal infections
January 25th 2022Research in the journal Cell Reports concludes that the discovery of a hormone-sensing pathway in Candida albicans, which enables the fungus to adapt to estrogen, could help explain gender biases linked to fungal infections and might provide an alternative approach to improving women's health.
Risks for recurrent VVC caused by non-albicans candida vs candida albicans
January 25th 2022Women with non-albicans Candida (NAC) vulvovaginal candidiasis (VVC) were nearly twice as likely to have multiple physician visits for recurring infections compared to women who had C. albicans (CA) VVC, according to a retrospective chart review in the Journal of Women’s Health.
Oral probiotics to prevent vulvovaginal infections in pregnant women
January 25th 2022An oral probiotic formula for the secondary prevention of vulvovaginal infections in pregnant women neither colonized in the vagina nor reduced the rate of repeated vulvovaginal infection, according to a study in the American Journal of Gynecology & Obstetrics.
Quality of life in women with deep infiltrating endometriosis and combined oral contraceptives
January 20th 2022There are a number of effective treatments, but a recent study sought to investigate how well oral contraceptives in particular could help reduce symptoms—while preserving sexual quality of life—in women with particularly severe forms of endometriosis.
Relugolix for treating uterine fibroids
January 19th 2022A phase 2, multicenter study has found relugolix (Myfembree; Myovant Sciences) significantly decreases menstrual blood loss in women with uterine leiomyomas and is mostly well tolerated. Relugolix is a small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist.
Microbial interplay of recurrent vulvovaginal candidiasis pathobiology
January 19th 2022A clinical study has confirmed that the pathophysiology of recurrent vulvovaginal candidiasis (RVVC) relies primarily on Candida albicans (C. albicans)-specific attributes like hyphal morphogenesis, biofilm formation and pathogenesis that differentiate it from other prominent non-albicans C. (NAC) species.
Treating recurrent vulvovaginal candidiasis with honey
January 18th 2022Because the mechanism of action of medical-grade honey (MGH) is based on enhancing wound healing and exerting strong broad-spectrum antimicrobial activity, MGH may also help to treat recurrent vulvovaginal candidiasis (RVVC), according to a review in the Journal of Fungi.
Impact of contraceptive coverage policies
January 13th 2022The findings support previous research demonstrating that increased access to emergency contraception does not compromise use of other more effective methods or lead to an increase in reported levels of unprotected sexual intercourse, according to Hawkins.