Vaginally applied progesterone gel provides higher endometrial levels and lower systemic levels of progesterone than intramuscularly administered progesterone, according to a prospective, randomized study involving 32 postmenopausal women. All of the participants used transdermal estradiol (50 ?g/day, a patch each week) for 2 weeks. In addition, they used 50 mg of either vaginal progesterone gel or IM progesterone in oil after 24 hours to oppose the transdermal estradiol.
Intentional weight loss linked to lower mortality in postmenopausal women
March 11th 2025A recent study shows that intentional weight loss significantly lowers all-cause, cancer, and cardiovascular mortality risks among postmenopausal women, highlighting the importance of targeted weight management.
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