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A recent study found that women with a history of gestational diabetes who sleep less or snore regularly face a significantly higher risk of developing type 2 diabetes later in life.

Sleep health linked to type 2 diabetes risk in women with gestational diabetes

A recent study shows that intentional weight loss significantly lowers all-cause, cancer, and cardiovascular mortality risks among postmenopausal women, highlighting the importance of targeted weight management.

Intentional weight loss linked to lower mortality in postmenopausal women

Shirley Wang, a PhD student in the School of Pharmacy at the University of Waterloo, discusses the findings on Levetiracetam’s safety during breastfeeding and how mothers can make informed decisions about medication use and infant health.

Researchers highlight risks of breastfeeding while taking Levetiracetam

A recent study reveals that offering financial incentives to pregnant women to quit smoking can lead to increased neonatal birth weight and improved health outcomes.

Financial rewards for smoking cessation boost neonatal birth weight

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A Psychedelic to Treat Postpartum Depression?

CMV: In the Know

RSV Roundtable

STIs

Supplement: Closing the Gap in Cervical Cancer Screening

Vaginismus: Managing a Misunderstood and Underdiagnosed Condition

Why vNOTES Make Sense for My Patients

1rem

Authors

Panelists discuss how nearly 46% of pregnancies in the US are unplanned. Although this rate has declined, the US still has one of the highest rates of unplanned pregnancies in the world, particularly affecting minority and disadvantaged communities.

Understanding the Rates of Unplanned Pregnancy in the United States

Saying "obstetrician-gynecologist" is a mouthful for most people, and it's probably the most abbreviated specialty in medicine, both spoken and written. However, there doesn't seem to be a consensus on how to pronounce OB-GYN. First, is it the two-syllable "O-B" or the monosyllabic "Ob"? Second, is it "gin" or "gyne" (like "Lyme")? I wonder if you have a preference. I know I do.

Almost nobody says "obstetrician-gynecologist" when speaking about these specialist physicians. But what's the "correct" way to pronounce OB/GYN?

Is It Ob-Gin or Ob-Gyne?

Empowering patients in urge urinary incontinence treatment

New pSNM system

Jannah Thompson, MD, FPMRS, from Trinity Health Urogynecology, discussed the health needs being solved by the Neuspera sacral neuromodulation (pSNM) system.

According to Thompson, the system allows patients to be active participants in their care, increasing their odds of continuing treatment long-term. While the study primarily focused on patients with urge urinary incontinence, results indicated the system may be used in a generalized population.

What unmet needs does the pSNM system solve?

Well, I think that the involvement of the patient in their therapy, because they actually have to hold the external stimulator up against them for 2 hours each day, makes them an active and willing participant in their care. Right now, the device we have is sort of a set it and forget it, but what happens is the patient then expects the doctor, or the doctor staff, to really be the sole driver of their symptom improvement, where this allows for the patient to be actively involved. I think some of our biases as doctors might be that a patient wouldn't want to do this, right? That they wouldn't want to have to do something 2 hours each day. But what we found is that a significant portion of the patients, 90% of them, continued to maintain daily stimulation of their therapy out 6 months, and they actually in making that behavior change where they're actually involved in their therapy may often lead these patients to be committed to trying other things to improve their symptoms. Maybe reducing acids, maybe working on constipation, maybe doing their physical therapy exercises, because they can see on a regular basis, that stimulation of this small wire inside actually produces less leakage and the results they want, thereby creating buy in and commitment on the patient's side, and also just having them an active and willing participant in their care.

What patient profile does this treatment apply to?

Well, the patient profile was actually broader than what we've seen in some of these other studies with sacral modulation in that it was women that were brought into the study, but they could have mixed incontinence, mixed incontinence meaning they could have urge and stress incontinence, or just urge incontinence. The study was looking at specifically urge incontinence episodes, and that's what we were targeting the therapy for. But what it allowed for is a much broader categorization of women that leak, which can make it more generalizable to the population that we see. And so, we're excited about this therapy that's now been submitted to the FDA for approval, and hopefully we will see that soon.

This video is part 2 of a 2-part series. Click 

Padron O. Treatment of OAB symptoms using Neuspera's ultra-minaturized system: 6-month results of the sans-UUI phase 2 study. Presented at: Society of Urodynamics Female Pelvic Medicine & Urogenital Reconstruction. Rancho Mirage, California. February 26-March 1, 2025.

Jannah Thompson, MD, FPMRS, discusses how the Neuspera sacral neuromodulation system encourages patient involvement, improving long-term treatment success and offering broader applicability for those with urge urinary incontinence.

Clinical

New pSNM system empowers patients in urge urinary incontinence treatment

A 27-year-old woman presents with an 18-month history of vulvar irritation. She is otherwise healthy except for episodes of depression. She has tried multiple agents for her condition including topical steroids, Vagisil, antibiotics, and fluconazole. She used oral steroids but developed knee pain. Tacrolimus has not helped. A biopsy revealed lichen simplex chronicus. Immunofluorescent studies were negative.

A 27-year-old woman presents with an 18-month history of vulvar irritation. She has tried multiple agents for her condition including topical steroids, Vagisil, antibiotics, and fluconazole without relief. What's your diagnosis?

Vulvar irritation in a 27-year-old woman

Name the part arrowed in these images in this late 3rd trimester fetal head.

Daily Dx: Normal Anatomy Quiz

This middle-aged woman has severe dysmenorrhea and pelvic discomfort. Ultrasound images of the uterus are shown. What is your diagnosis?

Daily Dx: Dysmenorrhea and Pelvic Discomfort

UUI management

, Jannah Thompson, MD, FPMRS, from Trinity Health Urogynecology, discussed a study evaluating the efficacy of the Neuspera sacral neuromodulation (pSNM) system in treating women with urgency urinary incontinence (UUI).

UUI is a condition where individuals experience sudden, uncontrollable urges to urinate, often resulting in leakage before reaching the bathroom. This condition significantly affects quality of life, leading to issues such as depression, anxiety, and social isolation. In the United States, approximately 1 in 5 women suffer from UUI, making it a widespread health concern.

Sacral neuromodulation (SNM) has been used as a treatment since 1997, with continuous technological advancements. The Neuspera pSNM system was designed to improve patient experience by offering a battery-free alternative to traditional SNM devices. This system consists of a mini percutaneous lead implanted near the sacral nerve, which stimulates the bladder nerve to reduce leakage episodes. Unlike conventional devices with batteries, this system requires external stimulation for 2 hours a day using a small, hands-free, and discreet wearable disc.

The study demonstrated promising results, showing that 84% of patients experienced at least a 50% reduction in leakage episodes. Among those who responded to the treatment, a significant proportion had even greater symptom improvement. Additionally, 42% of participants were completely dry, which exceeded the success rates of existing SNM systems. Furthermore, patients showed substantial improvements in quality of life, surpassing the minimum threshold by 3.5 times.

According to Thompson, the significance of these findings lies in the ability of this minimally invasive, battery-free device to deliver results comparable to or better than current SNM devices. This new system eliminates complications associated with battery-powered implants, such as movement, infection, discomfort, and visible bulging under the skin, which often require corrective surgery. By addressing these challenges, the Neuspera pSNM system represents a major advancement in treating UUI while enhancing patient comfort and convenience.

This video is part 1 of a 2-part series. Click 

A new study on the Neuspera sacral neuromodulation system reveals that 84% of patients experienced significant symptom improvement, offering a minimally invasive, battery-free solution for urgency urinary incontinence.

Lisa Bayer, MD, MPH

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