Contemporary OB/GYN week in review: Influenza, prediabetes, and more

Thank you for visiting the Contemporary OB/GYN® website. Take a look at some of our top stories from last week (Monday, September 23 - Friday, September 27, 2024), and click each link to read and watch anything you may have missed.

Maternal influenza linked to offspring seizure risk

The risk of childhood seizures is increased by maternal influenza infections during pregnancy, according to a recent study published in JAMA Network Open.

Higher rates of seizures were reported in the influenza group vs the control group, with 3.2% of infants in the influenza group developing seizures during follow-up. When evaluating this risk based on seizure type, an elevated risk did not remain for epilepsy, but the risk of febrile convulsions was significantly increased.

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Young adult prediabetes linked to future gestational diabetes

Prediabetes in young people may lead to adverse pregnancy outcomes later in life, according to a recent study from Mount Sinai.

The odds of having gestational diabetes at first birth were increased more than 2-fold among patients with preconception prediabetes, with an adjusted relative risk (aRR) of 2.21 compared to those with normoglycemia. Hypertensive disorder of pregnancy and preterm birth risks were also increased, both having an aRR of 1.18.

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Family history criteria used to predict breast cancer genetic risk variants

Patients with a familial risk of breast cancer can be identified using the electronic health record (EHR)-derived Seven-Question Family History Questionnaire (FHS7), according to a recent study published in JAMA Network Open.

A 3-fold increased risk of being BRCA1/2 positive was reported in both male and female patients with FHS7-positive status. When prescreening with FHS7, the number needed to test to detect a BRCA1/2-positive patient decreased from 128 to 53 among women and from 119 to 42 among men.

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Increasing birthweight over time reported

An increase in term birthweights over time has been observed since 1950, according to a recent study published in the American Journal of Obstetrics & Gynecology.

Data indicated a significant increase in the mean term birthweight of 4.74 g per year reported from municipality, community, or regional sources. When addressing geographical variations, this annual increase was 3.85 g.

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Similar live birth rates found for blastocyst vs cleavage stage embryo transfers in IVF treatment

Cumulative live birth rates are similar between blastocyst stage embryo transfers and cleavage stage embryo transfers in women with 4 or more embryos available during in vitro fertilization treatment, according to a recent study published in BMJ.

The intention-to-treat cumulative live birth rate was 58.9% in the blastocyst stage group and 58.4% in the cleavage stage group. With a difference of 0.4% and a risk ratio of 1.01, this data indicated no difference in live birth rates between groups.

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