Maternal Serum Marker Screening for Down Syndrome
July 22nd 2011Prenatal screening for Down syndrome is continuously being refined. Initially, the screen was limited to the health care provider's consideration of the mother's age at delivery, once the association between advanced maternal age (i.e. maternal age 35 or older at delivery) and increased risk for Down syndrome was recognized.
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Current Problems in Diagnostic Radiology covers important and controversial topics in radiology. Each issue presents important viewpoints from leading radiologists. High-quality reproductions of radiographs, CT scans, MR images, and sonograms clearly depict what is being described in each article. Also included are valuable updates relevant to other areas of practice, such as medical-legal issues or archiving systems.
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Maternal Position During the First Stage of Labor: A Systematic Review
July 21st 2011Policy makers and health professionals are progressively using evidence-based rationale to guide their decisions. There has long been controversy regarding which maternal position is more appropriate during the first stage of labor.
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Hands-on Approach During Breastfeeding Support in a Neonatal Intensive Care Unit
July 21st 2011Assisting mothers to breastfeed is not easy when babies experience difficulties. In a neonatal intensive care unit (NICU), nurses often help mothers by using hands-on-breast without their permission.
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Archive of Articles by David Hutchon, BSc, MB, ChB, FRCOG, UK OBGYN.net Editorial Advisor
July 21st 2011"Back to the Future" for Hermaani Boerhaave, or, "A rational way to generate ultrasound scan charts for estimating the date of delivery", by David Hutchon, BSc, MB, ChB, FRCOG How to use Bayes theorem to estimate sequential conditional risks. Odds ratio or Risk: that is the question! by David Hutchon, BSc, MB, ChB, FRCOG and A. Khattab, MD , Dept of Obstetrics and Gynaecology, Memorial Hospital, Darlington, UKOnline Calculators by Dr. Hutchon Down Syndrome risk calculator with growth calculator UK dates i.e. D/M/Y versionDown Syndrome risk calculator (using Hecht and Hook formula) with growth calculator UK dates i.e. D/M/Y versionDown Syndrome risk calculator with growth calculator US dates i.e. M/D/Y versionDown Syndrome risk calculator using gestation specific likelihood ratios for both CRL and BPD measurements. UK dates i.e. D/M/Y versionDown Syndrome risk calculator using gestation specific likelihood ratios for both CRL and BPD measurements. US dates i.e. M/D/Y versionDown Syndrome risk calculator with growth calculator FRENCH version translation by Docteur Eric Launay, Paris. Down Syndrome risk calculator with growth calculator SLOVENIA version translation by Mag. Stanko Pu?enjak, dr. med.Down Syndrome risk calculator with growth calculator ITALIAN version translation by D Spagnolo-HSRaffaele Milano.Software to generate your own customised EDD calculator (UK date style entry)Software to generate your own customised EDD calculator (US date style entry)Simple fetal weight calculatorChicken pox in pregnancy: - decision assistanceA customised (for fetal sex, parity, maternal age) EDD calculator for the Darlington population - (see how to make your own)Risk of malignancy index calculator for ovarian tumoursCritical Appraisal Page (with off-line calculator package) for single treatment trialCritical Appraisal Page (with off-line calculator package) for Diagnostic testCalculator for confidence intervals of relative risk.Calculator for confidence intervals of odds ratioA whole range of statistical calculatorsGenerates a table for any ultrasound parameter measurement converted to gestation using any polynomial equationGenerates a table for gestation to any ultrasound parameter measurement using any polynomial equationCalculator for risk of Down syndrome using second trimester US markers using work published by Greggory De VoreRisk of Abruptio Placentae as published by Baumann P et al Mathematic modeling to predict abruptio placentae. Am J Obstet Gynecol 2000;183:815-22
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First Trimester Nuchal Translucency Screening: Should It Be Standard of Care?
July 21st 2011Screening for Down syndrome has evolved significantly over the last number of years. Much research has been presented describing sonographic features that may be useful for the prenatal detection of Down syndrome, ranging from second trimester “soft markers” such as short femur, nuchal fold enlargement, or echogenic intracardiac foci, to first trimester features such as increased nuchal translucency or absent fetal nose bone.
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Ethical Issues in First-Trimester Screening
July 21st 2011It has previously been argued that “prenatal informed consent for sonogram be accepted as an indication for the prudent use of obstetric ultrasonography performed by qualified personnel.” We extend this argument to the use of ultrasound screening for aneuploidy in the first trimester.
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Benefits and Challenges of Transitioning Preterm Infants to At-Breast Feedings
July 21st 2011Upon hospital discharge it is not unusual for mothers of preterm infants to continue to meet all or most of their infants' nutritional needs through bottle feedings of expressed breast milk (EBM) because of infants' physiological immaturity and maternal concerns with an inadequacy of milk supply.
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Perioperative Complications in Infant Cleft Repair
July 20th 2011Cleft surgery in infants includes special risks due to the kind of the malformation. These risks can be attributed in part to the age and the weight of the patient. Whereas a lot of studies investigated the long-term facial outcome of cleft surgery depending on the age at operation, less is known about the complications arising during a cleft surgery in early infancy.
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Development of Antibodies to Human Embryonic Stem Cell Antigens
July 20th 2011Using antibodies to specific protein antigens is the method of choice to assign and identify cell lineage through simultaneous analysis of surface molecules and intracellular markers. Embryonic stem cell research can be benefited from using antibodies specific to transcriptional factors/markers that contribute to the "stemness" phenotype or critical for cell lineage.
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A Survey of Transcutaneous Blood Gas Monitoring Among European Neonatal Intensive Care Units
July 20th 2011PCO2 and PO2 are important monitoring parameters in neonatal intensive care units (NICU). Compared to conventional blood gas measurements that cause significant blood loss in preterms, transcutaneous (tc) measurements allow continuous, non-invasive monitoring of blood gas levels.
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Smoking and reproduction: The oviduct as a target of cigarette smoke
July 20th 2011The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes, transporting gametes in opposite directions to the site of fertilization, providing a suitable environment for fertilization and early development, and transporting preimplantation embryos to the uterus.
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Metabolic Syndrome Features and Risk of Neural Tube Defects
July 20th 2011Maternal obesity and pre-pregnancy diabetes mellitus, features of the metabolic syndrome (MetSyn), are individual risk factors for neural tube defects (NTD). Whether they, in combination with additional features of MetSyn, alter this risk is not known.
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Don't forget your Transvaginal probe
July 19th 2011Accurate diagnosis of congenital anomalies in the first trimester and early second trimester through the use of the transvaginal scan has been variously reported in the literature since the early 1990s. The feasibility of screening programmes for congenital abnormalities in the first trimester has also been recently reviewed by Chitty and Pandya.
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Chondroectodermal Dysplasia Diagnosed by First Trimester Ultrasound
July 19th 2011Chondroectodermal dysplasia, or Ellis-van Creveld syndrome, is an autosomal recessive disorder with an incidence of approximately 1 out of 150,000 live births. A higher prevalence has been reported among certain populations such as the Amish and the Arabs of the Gaza strip.
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Presumptive limb-body wall complex detected by ultrasonography
July 19th 2011Limb-body wall complex refers to a rare combination of disruptive and lethal abnormalities which start early in the gestational process. Abnormalities commonly associated with this disorder include cranio-facial abnormalities, scoliosis, ventral body wall defect (thoraco-abdominoschisis), limb deformations, short umbilical cord, and others.
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Cystic Fibrosis and Fertility Treatment
July 19th 2011Women with cystic fibrosis can have fertility treatment to help them have babies without any long-term adverse effects on either themselves or their children, according to new research presented at the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam today (Tuesday).
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Reduced Ovarian Reserve and Down's Syndrome
July 19th 2011Women who have a diminished number of eggs in their ovaries, either because they are older or for some other reason such as ovarian surgery, may be more at risk of a trisomic pregnancy than women with an ovarian reserve within the normal, fertile range.
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New Test for Both Genetic and Chromosomal Abnormalities in Embryos
July 19th 2011One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis.
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Reduce Multiple Pregnancies in PGD Cycles without Adversely Affecting Pregnancy Rates
July 19th 2011Transferring just one embryo at a time to a woman’s womb after embryos have undergone preimplantation genetic diagnosis (PGD) and freezing at the blastocyst stage has become a real option after researchers achieved pregnancy rates that were as good as those for blastocysts that had not had a cell removed for PGD before freezing.
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Easy Genetic Test Improves Pregnancy Rates in Older Women
July 19th 2011A new test examining chromosomes in human eggs a few hours after fertilisation can identify those that are capable of forming a healthy baby, a researcher told the 25th annual conference of the European Society of Human Reproduction and Embryology on 29 June.
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Ovarian Transplantation: First Baby is Born After New Technique
July 19th 2011A new technique for transplanting the ovaries of women who have lost their fertility as a result of cancer treatment was outlined to the 25th annual conference of the European Society of Human Reproduction and Embryology on Monday 29 June.
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