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Discover how innovative self-collection methods and the BD Onclarity HPV assay are breaking barriers in cervical cancer screening, empowering underserved communities with accessible and accurate care.

Transforming cervical cancer protection with the BD Onclarity HPV Assay

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Contemporary OB/GYN week in review: IUD placement, UTI misinformation, and more

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VMS and Menopause: KNDy Neurons, NK Receptors, and Practical Insights

Overview of KNDy neurons

KNDy neurons coexpress kisspeptin, neurokinin (NK) B, and dynorphin genes. How does NKB play a role in hormonal reproduction and VMS specifically?

Panelists discuss how KNDy neurons and NK receptors contribute to vasomotor symptoms (VMS) in menopause and explore emerging nonhormonal therapies, including fezolinetant and elinzanetant, for effective symptom management.

Panelists discuss how KNDy neurons, which coexpress kisspeptin, neurokinin B (NKB), and dynorphin genes, play a crucial role in hormonal reproduction and the development of vasomotor symptoms (VMS) in menopause.

Panelists discuss how neurokinin 3 (NK3) receptors contribute to vasomotor symptoms (VMS) and how antagonism of NK3 receptors with drugs like fezolinetant can effectively reduce VMS, while also exploring the dual receptor action of elinzanetant, which blocks both NK1 and NK3 receptors to improve VMS and associated sleep disturbances.

VMS Symptoms and Neurokinin Receptor Antagonists

Overview of KNDy neurons

EP: 1.Overview of KNDy neurons

EP: 2.VMS Symptoms and Neurokinin Receptor Antagonists